In ASP.NET we can show different master page on a single aspx page according to Browser type. Mean if you are viewing your application in IE then different look and if you are browsing your application in Mozilla then different look by setting these below line.
<%@ Page Title="" Language="C#" mozilla:MasterPageFile="~/MasterMozilla.master" ie:MasterPageFile="~/MasterIE.master" AutoEventWireup="true" CodeFile="Default.aspx.cs" Inherits="Default" %>