Visual Studio .vb open web site/page/file

Question

Hi all,
 
Very new to tinkering with Visual studio. I am trying the 2010 beta to see If I am able to fumble through a simple application.
I am wanting to do this, however have tried many ways and failed.
1./ from a button - on click, open a webpage.
2./ from a dropdown list - on click, open a webpage
3./ same as above but for a network/local file .pdf/.xls.whatever.
 
This is the start of the code
Private Sub Button1_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Button1.Click
however anything I try turns to crap.
 
Appreciate your kind assistance.