The best way to store some app specific data

Question

Hello  everyone.

I am developing an app(windows) which require to store folder paths selected by user for processing input files.What would be best option to store these names.I need help to choose from

1)writing to registry & then reading back
2)writing to app.config(am using vs 2005) & reading back (but config file shows the new entries only after restarting the app :-(.... )
3)rely on the Database.

Thanks for reading