Problem with position of controls on Windows form

Question

I am using Visual Studio 2015 Community to develop a Windows application..

I have two buttons at the bottom, right of the form and their anchors are set to Bottom, Right.

However when I save the solution and close Visual Studio and reopen the solution the buttons have moved up on the form. Every time I open the solution the buttons have moved up (Please see the picture). I have even tried locking the controls on the form.

 

Can anyone assist me with this?