Performance Concerns on deployment

Question

Hi, I have devoloped a application and I wanted it to deploy it over the network, so that whenever i make changes, i actually dont have to install it on each machine individually. So I changed the settings in the .NET Framework, where Full Trust is given to applications on Local LAN. But this makes my program to run really slowly. It takes atleast 2 minutes to load the program.This wasnt a problem when my network was in Novell, but when we changed the network to Microsoft AD, the program started running slowly. Any inputs on why is this happening