[.NET Core] Edit Excel by website

Question

(i'm french so excuse me for the errors) 

Hello,

I'm new on asp.net core and I wanted to know if it's possible to edit an excel document by a website ?

For example, if I select an Excel document (database) in a combobox and I click on a submit button, the 2nd page must display the variables of this document.

The client will fill these variable with textbox and click on print.

Thanks of the help !