If statement alternative to optimize code

Question

 

 

 

I can get fare From one city to To another city and selecting One Way , AC using following code

private void button1_Click(object sender, EventArgs e)    

     {   

          if (comboBox1.SelectedIndex == 0 && comboBox2.SelectedIndex == 0 && radioButton1.Checked &&  radioButton3.Checked) 

            {     

            MessageBox.Show("Your Fare is $225");   

            }        

 }

The problem is there will many many if satements incase if there are only 5 citis in combo box. What is the best way to choose different approcach to avoid if satemens.