how to deploye visual studio web application

Question

Hi,  I created a web project using visual studio 2017 "vs2017 ". I need to deploy it I got those options, I do not know what  to choose. please advise?  To publish via vs 2017 , I need to create   custom profile, I have two options of configuration 1. releaase 2. debug what is the difference between them . and what to choose Is there any resources available to read more about it. Ali