GUI layout changes when I switch computers

Ok, this is probably some incredibly basic thing, but I can't, for the life of me, seem to figure it out. I am doing a program on my desktop with Visual C#. All of the actual graphical stuff is being done visually, drag and drop. I've set all of the positions and sizes in the properties window for each item. However, when I view the program, or even load up the project, on my laptop all of those numbers change. Is there something that I am missing, a "fixed" setting, that keeps the program from doing that?