dependant checkboxlist in c# madness

Question

I have been working on dependant checkboxlists and its a total madness both in c# and vb.net 2013.

I cannot find a property or a method to check whether an item inside a checkboxlist is checked or unchecked.

How can i simply perform the detection?

Suppose i have six checkboxlists and every item in the second / third .... six checkboxlist is dependent on the preceeding element.

I want to add/remove elements in 2nd, 3rd ..... 6th checkboxlist when the user checks or unchecks a particular item inside a checkboxlist.

Example: Product, Color, Size...

Any example link in vb.net or c# would be appreciated.

Many Thanks