Best Way to Optimize C# Applications for Xeon 48-Core Processors?

Question

Hi everyone,

I’m working on a high-performance C# application that needs to take full advantage of a Xeon 48-Core processor for parallel processing and multi-threading. While I’ve used Task Parallel Library (TPL) and Parallel.ForEach before, I’m wondering if there are better ways to optimize performance on such a high-core-count CPU.

A few questions I have:

1. Threading vs. Asynchronous Programming – Which approach scales better on a 48-core Xeon processor?
2. Best Practices for CPU-bound workloads – Should I manually manage threads using ThreadPool or rely on .NET’s built-in parallelism?
3. NUMA Awareness – Does .NET handle Non-Uniform Memory Access (NUMA) optimization automatically, or should I manually allocate tasks to different CPU nodes?
4. Profiling Tools – What’s the best way to measure core utilization and performance bottlenecks in a highly parallelized C# application?

If anyone has experience optimizing .NET applications on high-core Xeon processors, I’d love to hear your insights!

Thanks in advance. ??