Designer Settings in SharePoint

SharePoint Designer Settings can be configured per web application level. Configuration is simply straightforward in SharePoint online environment.
 
These are the list of options available on the settings page. Just a tick mark would enable respective settings for you.
  1. Allow Site Owners and Designers to use SharePoint Designer in this SiteCollection
  2. Allow Site Owners and Designers to Detach Pages from the Site Definition
  3. Allow Site Owners and Designers to Customize Master Pages and PageLayouts
  4. Allow Site Owners and Designers to See the Hidden URL structure of their Web Site